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During the initial colonization phase, the mucus layer becomes more dynamic, turning over faster than usual
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17,228,235 These modifications considerably increase nuclease tolerance and prolong the half-life of nucleic acids while effectively avoiding the inflammatory reactions triggered by PS modification, demonstrating a higher safety and activity
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doi: 10.1002/nbm.1751 210 GlundeKJieCBhujwallaZM
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